%0 Journal Article %T Oropharyngeal candidiasis in children with lymphohematopoietic malignancies in Mashhad, Iran %J Current Medical Mycology %I Mazandaran University of Medical Sciences %Z 2423-3439 %A Berenji, Fariba %A Zabolinejad, Nona %A Badiei, Zahra %A Kakhi, soraya %A Andalib Aliabadi, Zohre %A Ganjbakhsh, Majid %D 2015 %\ 12/01/2015 %V 1 %N 4 %P 33-36 %! Oropharyngeal candidiasis in children with lymphohematopoietic malignancies in Mashhad, Iran %K Candida species %K Lymphohematopoietic malignancies %K Oral candidiasis %R 10.18869/acadpub.cmm.1.4.33 %X Background and Purpose: Over the past years, the role of fungi as a cause of nosocomial infections in hospitalized patients has been accentuated. Candida species constitute an important group of fungi causing diseases in immunocompromised patients. Oropharyngeal candidiasis continues to be a prevalent infection in immunodeficient patients. In this study, we aimed to determine the incidence of oropharyngeal candidiasis in children with lymphohematopoietic malignancies. Materials and Methods: In total, 102 patients with lymphohematopoietic malignancies and 50 healthy controls were examined in terms of Candida infections via direct sampling of the oropharyngeal cavity. Fresh smears were prepared with 10% potassium hydroxide and Gram staining was carried out. Subsequently, the obtained specimens were cultured on Sabouraud dextrose agar for further analysis. Results: The most common Candida species were Candida albicans (31%), other non-C. albicans species (14.7%), C. glabrata (6.8%), and C. krusei (0.98%) in the case group, while in the control group, other non-C. albicans species (10%) and C. albicans (8%) were the most common species. Conclusion: In the present study, Candida species were the most common fungal pathogens in pediatric cancer patients; therefore, efforts should be made to prevent fungemia and fungal pneumonia. Also, non-C. albicans species must be considered as a new risk factor for pediatric cancer patients. %U https://cmm.mazums.ac.ir/article_90310_31d408f699a9ae16196900c175e5aa0a.pdf