TY - JOUR ID - 133534 TI - Proven pulmonary aspergillosis in a COVID-19 patient: A case report JO - Current Medical Mycology JA - CMM LA - en SN - 2423-3439 AU - Salehi, Mohammadreza AU - Khodavaisy, Sadegh AU - Khajavirad, Nasim AU - Izadi, Alireza AU - Dehghan Manshadi, Seyed Ali AU - Abdollahi, Alireza AU - Aliramezani, Amir AU - Sasani, Elahe AU - Abdorahimi, Mahsa AU - Kiyaeie, Reyhaneh Sadat AU - Khosravany, Zohre AU - Getso, Muhammad AD - Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Pathology, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran AD - Central Laboratory, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Mycology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran AD - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran AD - Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Department of Medical Microbiology and Parasitology, College of Health Sciences, Faculty of Clinical Sciences, Y1 - 2021 PY - 2021 VL - 7 IS - 2 SP - 39 EP - 42 KW - Aspergillosis KW - Aspergillus tubingensis KW - COVID-19 DO - 10.18502/CMM.7.2.7031 N2 - Background and Purpose: Coronavirus disease 2019 (COVID-19) has become a significant clinical challenge in healthcare settings all over the world. Critically ill COVID-19 patients with acute respiratory distress syndrome may be at increased risk of co-infection with pulmonary aspergillosis. This study aimed to describe a clinical case of proven pulmonary aspergillosis caused by Aspergillus tubingensis in a 59-year-old man with a history of hospitalization due to COVID-19 infection.Case report: The Covid-19 infection was confirmed by positive nasopharyngeal polymerase chain reaction. He had a cavitary lesion measured 20 mm in diameter with intracavitary soft tissue density in the left lung in the first chest computerized tomography scan. After 25 days, he showed two cavitary lesions in both lungs which raised suspicion of fungal infection; hence, the patient underwent a trans-thoracic biopsy of the cavitary lesion. The direct examination and culture of the biopsy material revealed Aspergillus species. To confirm the Aspergillus species identification, the beta-tubulin region was sequenced. The patient was treated with oral voriconazole.Conclusion: This report underlined the importance of early diagnosis and management of invasive fungal infections in severe COVID-19 patients  UR - https://cmm.mazums.ac.ir/article_133534.html L1 - https://cmm.mazums.ac.ir/article_133534_4618c7a143510df26f5628d5cf53382f.pdf ER -