TY - JOUR ID - 139758 TI - Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers JO - Current Medical Mycology JA - CMM LA - en SN - 2423-3439 AU - Gnoni, Martin AU - McCann, Timothy AU - Riva-Moscoso, Adrian AU - Príncipe-Meneses, Fortunato S AU - Chambergo-Michilot, Diego AD - Department of Internal Medicine, Good Samaritan Hospital, Cincinnati, Ohio, United States of America AD - Trihealth Internal Medicine, Infectious Diseases, Cincinnati, Ohio, United States of America AD - School of Medicine, Peruvian University of Applied Sciences, Lima, Peru AD - School of Medicine, Scientific University of the South, Lima, Peru Y1 - 2021 PY - 2021 VL - 7 IS - 4 SP - 34 EP - 37 KW - Fungal KW - Histoplasmosis KW - Ohio KW - Spores KW - United States DO - 10.18502/cmm.7.4.8409 N2 - Background and Purpose: Histoplasma capsulatum is the cause of a prevalent fungal disease in certain regions in the United States of America, like Ohio and the Mississippi River. Its clinical manifestations range from asymptomatic to life-threatening diseases,according to the immune system. A definitive diagnosis is made by biopsy.Case report: Two middle-aged brothers presented with a nine-day history of severe progressive dyspnea. Both were living in Cincinnati, Ohio, and encountered bird droppings 7 days prior to symptoms while working on a roofing project. It should be mentioned that they were not wearing masks. After extensive testing, they were diagnosed with acute pulmonary histoplasmosis. Both were successfully treated with azole-derivative fungal therapy.Conclusion: This is the first case of histoplasmosis acquired through occupational exposure related to roofing and is unique given the two patients were siblings  UR - https://cmm.mazums.ac.ir/article_139758.html L1 - https://cmm.mazums.ac.ir/article_139758_01be00210bd77ba588675d0d5f1832a6.pdf ER -