Volume 3, Issue 3 (September 2017)                   Curr Med Mycol 2017, 3(3): 27-30 | Back to browse issues page

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Ismail M T, Alkafri A, Ismail M. Otomycosis in Damascus, Syria: Etiology and clinical features. Curr Med Mycol. 2017; 3 (3) :27-30
URL: http://cmm.mazums.ac.ir/article-1-155-en.html
Abstract:   (965 Views)
Background and Purpose: Otomycosis is a fungal infection that frequently involves the external auditory canal. The epidemiologic data on the etiologic agents of otomycosis in Syria are very limited. In this study, we aimed to determine the fungal agents, gender distribution, and clinical presentation of otomycosis.
Materials and Methods: Two hundred and ninety nine patients (153 [51.17%] male and 146 [48.83%] female) clinically prediagnosed as otomycosis were studied at Al-mouassat University Hospital and ENT Crescent Syrian Clinic. Clinical samples were collected from the ear discharges and cultured on Sabouraud Agar.
Results: Otomycosis was diagnosed in 70 (23.4%) cases, with the highest prevalence in males aged 16-75 years (73.6%). The isolation rates of mold and yeast fungi were 75.7% and 24.3%, respectively. The most common presentations were otorrhea (98.66%), otalgia (18.06%), and hearing loss (6.35%). Our results showed that 64.28% of otomycosis agents were Aspergillus species. A. niger was the most common agent (45.7%), and 24.3% of the pathogens were C. albicans.
Conclusion: Otomycosis agents most commonly belonged to the genus of Aspergillus followed by Candida, which should be seriously considered by physicians for appropriate treatment.
Full-Text [PDF 417 kb]   (805 Downloads)    
Type of Study: Original Articles | Subject: Medical Mycology
Received: 2017/09/16 | Accepted: 2017/12/9 | Published: 2018/02/17

1. Barati B, Okhovvat SA, Goljanian A, Omrani MR. Otomycosis in central Iran: a clinical and mycological study. Iran Red Crescent Med J. 2011; 13(12):873-6.
2. Agarwal P , Devi S L. Otomycosis in a Rural Community Attending a Tertiary Care Hospital: Assessment of Risk Factors and Identification of Fungal and Bacterial Agents. J Clin Diagn Res. 2017 Jun; 11(6): DC14–18. [DOI:10.7860/JCDR/2017/25865.10068]
3. Ho T, Vrabec JT, Yoo D, Coker NJ. Otomycosis: clinical features and treatment implications. Otolaryngol Head Neck Surg 2006; Nov;135(5):787-91 [DOI:10.1016/j.otohns.2006.07.008]
4. Pontes ZB, Silva AD, Lima Ede O, Guerra Mde H, Oliveira NM, Carvalho Mde F, et al. Otomycosis: a retrospective study. Braz J Otorhinolaryngol. 2009;75(3):367–70. [DOI:10.1590/S1808-86942009000300010]
5. Munguia R, Daniel SJ.Ototopical antifungals and otomycosis: a review. Int J Pediatr Otorhinolaryngol. 2008; 72(4):453-9. [DOI:10.1016/j.ijporl.2007.12.005]
6. Badali H, Fakhim H, Zarei F, Nabili M, Vaezi A, Poorzad N, et al. In vitro activities of five antifungal drugs against opportunistic agents of Aspergillus Nigri Complex. Mycopathologia. 2016; 181(3-4):235-40. [DOI:10.1007/s11046-015-9968-0]
7. Yaganeh Moghadam A, Asadi MA, Dehghani R, Zarei Mahmoudabadi A, Rayegan F, Hooshyar H, et al. Evaluating the effect of a mixture of alcohol and acetic acid for otomycosis therapy. Jundishapur J Microbiol.2010; 3(2):66-70.
8. Gharaghani M, Seifi Z, Zarei Mahmoudabadi A. Otomycosis in iran: a review.Mycopathologia. 2015 Jun;179(5-6):415-24. [DOI:10.1007/s11046-015-9864-7]
9. Koenig H. Guide de mycologie médicale. Paris: Ellipses; 1995.
10. Vennewald I, Klemm E. Otomycosis: Diagnosis and treatment. Clin Dermatol. 2010;28(2):202–11. [DOI:10.1016/j.clindermatol.2009.12.003]
11. Dubach P, Mantokoudis G, Caversaccio M. Ear canal cholesteatoma: meta-analysis of clinical characteristics with update on classification, staging and treatment. Curr Opin Otolaryngol Head Neck Surg. 2010;18(5):369–76. [DOI:10.1097/MOO.0b013e32833da84e]
12. Aneja KR, Sharma C, Joshi R. Fungal infection of the ear: a common problem in the north eastern part of Haryana. Int J Pediatr Otorhinolaryngol. 2010;74(6):604–7. [DOI:10.1016/j.ijporl.2010.03.001]
13. Viswanatha B, Naseeruddin K. Fungal infections of the ear in immunocompromised host: a review. Mediterr J Hematol Infect Dis. 2011;3(1):e2011003. [DOI:10.4084/mjhid.2011.003]
14. Jackman A, Ward R, April M, Bent J. Topical antibiotic induced otomycosis. Int J Pediatr Otorhinolaryngol. 2005;69(6):857–60. [DOI:10.1016/j.ijporl.2005.01.022]
15. Hueso Gutierrez P, Jimenez Alvarez S, Gil-Carcedo Sanudo E, Gil-Carcedo Garcia LM, Ramos Sanchez C, Vallejo Valdezate LA. Presumption diagnosis: otomycosis. A 451 patients study. Acta Otorrinolaringol Esp. 2005;56(5):181–6. [DOI:10.1016/S0001-6519(05)78597-6]
16. Ozcan KM, Ozcan M, Karaarslan A, Karaarslan F. Otomycosis in Turkey: predisposing factors, aetiology and therapy. J Laryngol Otol. 2003;117(1):39–42. [DOI:10.1258/002221503321046621]
17. Fasunla J, Ibekwe T, Onakoya P. Otomycosis in western Nigeria. Mycoses. 2008;51(1):67–70.
18. Pardhan B, Tuladhar NR, Amatya RM. Prevalence of otomycosis in outpatientdepartment of otolaryngology in Tribhuvan University Teaching Hospital, Kathmandu,Nepal. Ann Otol Rhinol Laryngol. 2003;112(4):384-7. [DOI:10.1177/000348940311200416]
19. Anwar K and Gohar M S. Otomycosis; clinical features, predisposing factors and treatment implications. Pak J Med Sci. 2014 May-Jun; 30(3): 564–7.
20. Kumar A. Fungal spectrum in otomycosis patients. JK Sci. 2005;7(3):152–5.
21. Kazemi A, Majidinia M, Jaafari A, Ayatollahi Mousavi SA, Zarei Mahmoudabadi A, Alikhah H. Etiologic Agents of Otomycosis in the North-Western Area of Iran. Jundishapur J Microbiol. 2015 Sep 8;8(9):e 21776.
22. Kiakojuri K, Rajabni R, Jalili B, Khafri S, Omran S M. Otomycosis in Adolescent Patients Referred to the Therapeutic Centers in Babol City, Iran. Jundishapur J Microbiol. 2015 May; 8(5): e17138. [DOI:10.5812/jjm.8(5)2015.17138]
23. Morozova OV, Krasnozhen VN, Glushko NI, Khaldeeva EV, Lisovskaya SA. The role of mycological culture studies in diagnostics of otomycoses].Vestn Otorinolaringol. 2015;80(4):41-3. [DOI:10.17116/otorino201580441-43]
24. Fayemiwo SA1, Ogunleye VO, Adeosun AA, Bakare RA. Prevalence of otomycosis in Ibadan: a review of laboratory reports. Afr J Med Med Sci. 2010 Dec;39 Suppl:219-22.
25. Değerli K, Ecemiş T, Günhan K, Başkesen T, Kal E. Agents of otomycosis in Manisa region, Turkey, 1995-2011]. Mikrobiyol Bul. 2012 Jan;46(1):79-84.
26. Aneja KR, Sharma C, Joshi R. Fungal infection of the ear: a common problem in the north eastern part of Haryana. Int J Pediatr Otorhinolaryngol. 2010;74(6):604–7 [DOI:10.1016/j.ijporl.2010.03.001]
27. Cheffins T, Heal C, Rudolphy S. Acute otitis externa: management by GPs in North Queensland. Aust Fam Physician. 2009;38(4):262–3
28. Jia X, Liang Q, Chi F, Cao W. Otomycosis in Shanghai: aetiology, clinical features and therapy. Mycoses. 2012;55(5):404–9. [DOI:10.1111/j.1439-0507.2011.02132.x]
29. Saki N, Rafiei A, Nikakhlagh S, Amirrajab N, Saki S. Prevalence of otomycosis in Khouzestan Province, south-west Iran. J Laryngol Otol. 2013; 127(1):25-7. [DOI:10.1017/S0022215112002277]
30. Abdelazeem M, Gamea A, Mubarak H, Elzawawy N Epidemiology, causative agents, and risk factors affecting human otomycosis infections.Turk J Med Sci. 2015;45(4):820-6. [DOI:10.3906/sag-1407-17]
31. Itah AY, Ekpombok MU. Pollution status of swimming pools in south-south zone of south-eastern Nigeria using microbiological and physicochemical indices. Southeast Asian J Trop Med Public Health. 2004 Jun;35(2):488-93.
32. Martin TJ, Kerschner JE, Flanary VA. Fungal causes of otitis externa and tympanostomy tube otorrhea. Int J Pediatr Otorhinolaryngol. 2005 Nov;69(11):1503-8. [DOI:10.1016/j.ijporl.2005.04.012]
33. Szigeti G, Sedaghati E, Mahmoudabadi Zarei A, Naseri A, Kocsube S. Species assignment and antifungal susceptibilities of black aspergilli recovered from otomycosis cases in Iran. Mycoses. 2011;55:333–8. [DOI:10.1111/j.1439-0507.2011.02103.x]
34. Miertusova S, Simaljakova M. Yeasts and fungi isolated at the mycology laboratory of the First Dermatovenerology Clinic of the Medical Faculty Hospital of Comenius University in Bratislava 1995-2000 . Epidemiol Mikrobiol Imunol. 2003;52(2):76–80.

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