Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient

Authors

1 Infectious diseases and tropical medicine research center , Shahid Beheshti university of medical sciences,Tehran, Iran

2 Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 Infectious diseases and tropical medicine research center , Shahid Beheshti university of medical sciences ,Tehran, Iran

4 Department of microbiology, Medical school,Shahid Beheshti university of medical sciences , Tehran, Iran

Abstract

Background and Purpose: Fusarium species is an opportunistic mold that causes disseminated infections in immunocompromised patients. Given the high mortality rate of this infection, it is important to make a definite diagnosis when encountering suspected cases.

Case report: Herein, we presented a 35-year-old man diagnosed with acute myeloid leukemia with a prolonged febrile neutropenic period and ecthyma gangrenosum-like lesions, along with fungemia and disseminated fusariosis. The patient died despite receiving combination therapy, perhaps due to the nonrecovery of neutrophil.

Conclusion: Ecthyma gangrenosum-like lesions due to disseminated fusariosis might be easily misdiagnosed. Consequently, more attention should be paid to the cutaneous lesions in immunocompromised patients.

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