Volume 3, Issue 2 (June 2017)                   Curr Med Mycol 2017, 3(2): 33-37 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aghaei Gharehbolagh S, Nasimi M, Agha Kuchak Afshari S, Ghasemi Z, Rezaie S. First case of superficial infection due to Naganishia albida (formerly Cryptococcus albidus) in Iran: A review of the literature . Curr Med Mycol. 2017; 3 (2) :33-37
URL: http://cmm.mazums.ac.ir/article-1-158-en.html
Abstract:   (851 Views)
Background and Purpose: Naganishia albida (formerly Cryptococcus albidus) is a non-neoformans cryptococcal species rarely isolated as a human pathogen.
Case report: Herein, we present the case of a 26-year-old Iranian man with a superficial cutaneous lesion in the axilla. The initial treatment for pityriasis versicolor by clotrimazole was unsuccessful. We performed skin sampling based on the standard protocol and conducted further investigations by the conventional laboratory tests and molecular analysis of the skin samples. All the mentioned analyses revealed N. albida as the causative agent of infection. The minimum inhibitory concentration (MIC) analysis was carried out for the isolated agent, and the patient was treated using 100 mg daily of oral itraconazole.
Conclusion: N. albida can be the causative agent of some superficial infections. This is the first report on the successful detection and treatment of a superficial skin infection due to N. albida by oral itraconazole.  
Full-Text [PDF 513 kb]   (301 Downloads)    
Type of Study: Case report | Subject: Medical Mycology
Received: 2017/09/27 | Accepted: 2017/11/29 | Published: 2018/01/6

References
1. Faress JA, Hejal R. Pulmonary crytpococcosis due to C. albidus in a patient on Infliximab. Chest. 2004; 126(4):987S-8. [DOI:10.1378/chest.126.4_MeetingAbstracts.987S]
2. de Castro LE, Sarraf OA, Lally JM, Sandoval HP, Solomon KD, Vroman DT. Cryptococcus albidus keratitis after corneal transplantation. Cornea. 2005; 24(7):882-3. [DOI:10.1097/01.ico.0000157404.34774.1a]
3. Hagen F, Lumbsch HT, Arsic Arsenijevic V, Badali H, Bertout S, Billmyre RB, et al. Importance of resolving fungal nomenclature: the case of multiple pathogenic species in the Cryptococcus genus. Msphere. 2017; 2(4):e00238-17. [DOI:10.1128/mSphere.00238-17]
4. Burnik C, Altintaş N, Özkaya G, Serter T, Selcuk Z, Firat P, et al. Acute respiratory distress syndrome due to Cryptococcus albidus pneumonia: case report and review of the literature. Med Mycol. 2007; 45(5):469-73. [DOI:10.1080/13693780701386015]
5. Khawcharoenporn T, Apisarnthanarak A, Mundy LM. Non-neoformans cryptococcal infections: a systematic review. Infection. 2007; 35(2):51-8. [DOI:10.1007/s15010-007-6142-8]
6. Kano R, Kitagawa M, Oota S, Oosumi T, Murakami Y, Tokuriki M, et al. First case of feline systemic Cryptococcus albidus infection. Med Mycol. 2008; 46(1):75-7. [DOI:10.1080/13693780701541106]
7. Labrecque O, Sylvestre D, Messier S. Systemic Cryptococcus albidus infection in a Doberman Pinscher. J Vet Diagn Invest. 2005; 17(6):598-600. [DOI:10.1177/104063870501700615]
8. Huang YH, Lin IH, Chang TC, Tseng SH. Early diagnosis and successful treatment of Cryptococcus albidus keratitis: a case report and literature review. Medicine. 2015; 94(19):e885. [DOI:10.1097/MD.0000000000000885]
9. Liu Y, Ma S, Wang X, Xu W, Tang J. Cryptococcus albidus encephalitis in newly diagnosed HIV-patient and literature review. Med Mycol Case Rep. 2014; 3:8-10. [DOI:10.1016/j.mmcr.2013.11.002]
10. Hoang JK, Burruss J. Localized cutaneous Cryptococcus albidus infection in a 14-year-old boy on etanercept therapy. Pediatr Dermatol. 2007; 24(3):285-8. [DOI:10.1111/j.1525-1470.2007.00404.x]
11. Huang W, Liao G, Baker GM, Wang Y, Lau R, Paderu P, et al. Lipid flippase subunit Cdc50 mediates drug resistance and virulence in Cryptococcus neoformans. MBio. 2016; 7(3):e00478-16. [DOI:10.1128/mBio.00478-16]
12. Smith KD, Achan B, Hullsiek KH, McDonald TR, Okagaki LH, Alhadab AA, et al. Increased antifungal drug resistance in clinical isolates of Cryptococcus neoformans in Uganda. Antimicrob Agents Chemother. 2015; 59(12):7197-204. [DOI:10.1128/AAC.01299-15]
13. Yamada Y, Makimura K, Merhendi H, Ueda K, Nishiyama Y, Yamaguchi H, et al. Comparison of different methods for extraction of mitochondrial DNA from human pathogenic yeasts. Jpn J Infect Dis. 2002; 55(4):122-5.
14. Zarrinfar H, Kaboli S, Dolatabadi S, Mohammadi R. Rapid detection of Candida species in bronchoalveolar lavage fluid from patients with pulmonary symptoms. Braz J Microbiol. 2016; 47(1):172-6. [DOI:10.1016/j.bjm.2015.02.001]
15. Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution anti-fungal susceptibility testing of yeasts; approved standard-third edition, M27–A3. Wayne: CLSI; 2008.
16. Narayan S, Batta K, Colloby P, Tan C. Cutaneous cryptococcus infection due to C. albidus associated with Sezary syndrome. Br J Dermatol. 2000; 143(3):632-4. [DOI:10.1111/j.1365-2133.2000.03724.x]
17. Lee YA, Kim HJ, Lee TW, Kim MJ, Lee MH, Lee JH, et al. First report of Cryptococcus albidus-induced disseminated cryptococcosis in a renal transplant recipient. Korean J Intern Med. 2004; 19(1):53-7. [DOI:10.3904/kjim.2004.19.1.53]
18. Endo JO, Klein SZ, Pirozzi M, Pirozzi C, Hull CM. Generalized Cryptococcus albidus in an immuno-suppressed patient with palmopustular psoriasis. Cutis. 2011; 88(3):129-32.
19. Cleveland KO, Gelfand MS, Rao V. Posaconazole as successful treatment for fungemia due to Cryptococcus albidus in a liver transplant recipient. QJM. 2013; 106(4):361-2. [DOI:10.1093/qjmed/hcs133]
20. Krumholz RA. Pulmonary cryptococcosis. A case due to Cryptococcus albidus. Am Rev Respir Dis. 1972; 105(3):421-4.
21. da Cunha T, Lusins J. Cryptococcus albidus meningitis. South Med J. 1973; 66(11):1230. [DOI:10.1097/00007611-197311000-00006]
22. Melo JC, Srinivasan S, Scott ML, Raff MJ. Cryptococcus albidus meningitis. J Infect. 1980; 2(1):79-82. [DOI:10.1016/S0163-4453(80)91865-4]
23. Gluck JL, Myers JP, Pass LM. Cryptococcemia due to cryptococcus albidus. South Med J. 1987; 80(4):511-3. [DOI:10.1097/00007611-198704000-00024]
24. Lin SR, Peng CF, Yang SA, Yu HS. Isolation of Cryptococcus albidus var. albidus in patient with pemphigus foliaceus. Gaoxiong Yi Xue Ke Xue Za Zhi. 1989; 5(2):126-8.
25. Horowitz ID, Blumberg EA, Krevolin L. Cryptococcus albidus and mucormycosis empyema in a patient receiving hemodialysis. South Med J. 1993; 86(9):1070-2. [DOI:10.1097/00007611-199309000-00022]
26. Loison J, Bouchara JP, Gueho E, de Gentile L, Cimon B, Chennebault JM, et al. First report of Cryptococcus albidus septicaemia in an HIV patient. J Infect. 1996; 33(2):139-40. [DOI:10.1016/S0163-4453(96)93176-X]
27. Wells GM, Gajjar A, Pearson TA, Hale KL, Shenep JL. Pulmonary cryptosporidiosis and cryptococcus albidus fungemia in a child with acute lymphocytic leukemia. Med Pediatr Oncol. 1998; 31(6):544-6. https://doi.org/10.1002/(SICI)1096-911X(199812)31:6<544::AID-MPO20>3.0.CO;2-N [DOI:10.1002/(SICI)1096-911X(199812)31:63.0.CO;2-N]
28. Ragupathi L, Reyna M. Case report of Cryptococcus albidus peritonitis in a peritoneal dialysis patient and a review of the literature. Perit Dial Int. 2015; 35(4):421-7. [DOI:10.3747/pdi.2013.00134]
29. Papadopoulou M, Kimouli M, Spanou S, Isidorou M, Rekliti N, Antonogeorgos G, et al. Cryptococcus albidus fungemia in premature neonate. Acta Paediatr. 2011; 100:73.
30. Garelick JM, Khodabakhsh AJ, Lopez Y, Bamji M, Lister M. Scleral ulceration caused by Cryptococcus albidus in a patient with acquired immune deficiency syndrome. Cornea. 2004; 23(7):730-1. [DOI:10.1097/01.ico.0000126322.13143.7b]
31. Gyimesi A, Bator A, Gorog P, Telegdy E, Szepes E, Kappeter A, et al. Cutaneous Cryptococcus albidusnfection. Int J Dermatol. 2017; 56(4):452-4. [DOI:10.1111/ijd.13576]
32. Custis LP, Haller JA, de Juan E Jr. An unusual case of cryptococcal endophthalmitis. Retina. 1995; 15(4):300-4. [DOI:10.1097/00006982-199515040-00006]
33. Ramchandren R, Gladstone DE. Cryptococcus albidus infection in a patient undergoing autologous progenitor cell transplant. Transplantation. 2004; 77(6):956. [DOI:10.1097/01.TP.0000118412.92283.32]

Add your comments about this article : Your username or Email:
CAPTCHA code

Send email to the article author


© 2015 All Rights Reserved | Current Medical Mycology