Volume 1, Number 1 (March 2015)                   mazu-cmm 2015, 1(1): 42-48 | Back to browse issues page



DOI: 10.18869/acadpub.cmm.1.1.42

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Khodavaisy S, Mortaz E, Mohammadi F, Aliyali M, Fakhim H, Badali H. Pneumocystis jirovecii colonization in Chronic Obstructive Pulmonary Disease (COPD). mazu-cmm. 2015; 1 (1) :42-48
URL: http://cmm.mazums.ac.ir/article-1-34-en.html

Abstract:   (1920 Views)

Chronic obstructive pulmonary disease (COPD) is associated with a chronic inflammatory response in airways and lung parenchyma that results in significant morbidity and mortality worldwide. Cigarette smoking considered as an important risk factor plays a role in pathogenesis of disease. Pneumocystis jirovecii is an atypical opportunistic fungus that causes pneumonia in immunosuppressed host, although the low levels of its DNA in patients without signs and symptoms of pneumonia, which likely represents colonization. The increased prevalence of P. jirovecii colonization in COPD patients has led to an interest in understanding its role in the disease. P. jirovecii colonization in these patients could represent a problem for public health since colonized patients could act as a major reservoir and source of infection for susceptible subjects. Using sensitive molecular techniques, low levels of P. jirovecii DNA have been detected in the respiratory tract of certain individuals. It is necessary to elucidate the role of P. jirovecii colonization in the natural history of COPD patients in order to improve the clinical management of this disease. In the current review paper, we discuss P. jirovecii colonization in COPD patients.

Full-Text [PDF 800 kb]   (929 Downloads)    
Type of Study: Reviews | Subject: Medical Mycology
Received: 2014/09/27 | Accepted: 2015/01/3 | Published: 2015/01/12

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Current Medical Mycology