First report of Candida sojae sepsis in a preterm infant; A new fungal threat in neonatal care

Document Type : Case report

Authors

1 Department of Neonatology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye

2 Department of Clinical Microbiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye

10.22034/cmm.2025.345269.1565

Abstract

Background and Purpose: Very low birth weight neonates are at high risk of invasive infections, including invasive candidiasis, which is associated with significant morbidity and mortality. Although Candida albicans, Candida parapsilosis, and Candida tropicalis are well-known fungal pathogens in these neonates, Candida sojae has been recently reported as a new agent of invasive candidiasis.
Case report: This study aimed to report a very low birth weight preterm neonate who had septicemia due to C. sojae. In this neonate, immature immune and gastrointestinal systems, prolonged parenteral nutrition due to feeding intolerance, central venous catheter, and broad-spectrum antibiotic use were risk factors leading to sepsis with C. sojae. The neonate recovered completely with timely antifungal treatment.
Conclusion: This case emphasized the need to be aware of C. sojae as an emerging neonatal pathogen in preterm infants.

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Current Medical Mycology
Volume 10, Continuous
2024
Pages 1-4

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History

  • Receive Date: 22 July 2024
  • Revise Date: 24 December 2024
  • Accept Date: 07 January 2025
  • Publish Date: 01 February 2024

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