Niosome-loaded antifungal drugs as an effective nanocarrier system: A mini review

Authors

1 Department of Medical Nanotechnology, Schools of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran

2 Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

3 5- Invasive Fungi Research Center (IFRC)/Department of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari

4 Immunogenetics Research Center, Department of Medical Nanotechnology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

Abstract

Skin is an important organ of the body due to offering an accessible and convenient site for drug administration. One of the disadvantages of transdermal drug delivery is the low penetration rate of drugs through the skin. Over the past decades, nanoparticles have been used as drug delivery systems to increase therapeutic effects or reduce toxicity. Encapsulation of drugs in nanoparticulate vesicles simplifies the transports of drugs into and across the skin.
Niosome nanoparticles are among these drug delivery systems, which have numerous applications in drug delivery and targeting. Niosomes are frequently used for loading drugs serving different purposes (e.g., anticancer, antiviral, and antibacterial agents). In recent years, there has been much research on the use of niosomal systems for the delivery of fungal drugs. A review of the literature investigating the advantages of niosomes in antifungal drug delivery can elucidate the efficiency and superiority of this nanocarrier over other nanocarriers.
 

Keywords

Current Medical Mycology
Volume 4, Issue 4
December 2018
Pages 31-36

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History

  • Receive Date: 09 July 2019
  • Revise Date: 09 October 2020
  • Accept Date: 09 July 2019
  • Publish Date: 01 December 2018

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